The design complexity of CPUs increased as various technologies facilitated building smaller and more reliable electronic devices. The first such improvement came with the advent of the transistor. Transistorized CPUs during the 1950s and 1960s no longer had to be built out of bulky, unreliable, and fragile switching elements like vacuum tubes and electrical relays. With this improvement more complex and reliable CPUs were built onto one or several printed circuit boardscontaining discrete (individual) components.
During this period, a method of manufacturing many transistors in a compact space gained popularity. The integrated circuit (IC) allowed a large number of transistors to be manufactured on a single semiconductor-based die, or "chip." At first only very basic non-specialized digital circuits such as NOR gates were miniaturized into ICs. CPUs based upon these "building block" ICs are generally referred to as "small-scale integration" (SSI) devices. SSI ICs, such as the ones used in the Apollo guidance computer, usually contained transistor counts numbering in multiples of ten. To build an entire CPU out of SSI ICs required thousands of individual chips, but still consumed much less space and power than earlier discrete transistor designs. As microelectronic technology advanced, an increasing number of transistors were placed on ICs, thus decreasing the quantity of individual ICs needed for a complete CPU. MSI and LSI (medium- and large-scale integration) ICs increased transistor counts to hundreds, and then thousands.
In 1964 IBM introduced its System/360 computer architecture which was used in a series of computers that could run the same programs with different speed and performance. This was significant at a time when most electronic computers were incompatible with one another, even those made by the same manufacturer. To facilitate this improvement, IBM utilized the concept of a microprogram (often called "microcode"), which still sees widespread usage in modern CPUs . The System/360 architecture was so popular that it dominated the mainframe computer market for decades and left a legacy that is still continued by similar modern computers like the IBM zSeries. In the same year (1964), Digital Equipment Corporation (DEC) introduced another influential computer aimed at the scientific and research markets, the PDP-8. DEC would later introduce the extremely popular PDP-11 line that originally was built with SSI ICs but was eventually implemented with LSI components once these became practical. In stark contrast with its SSI and MSI predecessors, the first LSI implementation of the PDP-11 contained a CPU composed of only four LSI integrated circuits .
Transistor-based computers had several distinct advantages over their predecessors. Aside from facilitating increased reliability and lower power consumption, transistors also allowed CPUs to operate at much higher speeds because of the short switching time of a transistor in comparison to a tube or relay. Thanks to both the increased reliability as well as the dramatically increased speed of the switching elements (which were almost exclusively transistors by this time), CPU clock rates in the tens of megahertz were obtained during this period. Additionally while discrete transistor and IC CPUs were in heavy usage, new high-performance designs like SIMD (Single Instruction Multiple Data) vector processors began to appear. These early experimental designs later gave rise to the era of specialized supercomputers like those made by Cray Inc.